Karol G consigue su primer número uno con 'Tusa', junto con Nicki Minaj. Además hay cinco nuevas entradas en lista.
| Nº | TÍTULO / ARTISTA | SEM | MÁX |
| 1 | Tusa / Karol G ft. Nicki Minaj | 7 | 1 |
| 2 | Blinding lights / The Weeknd | 8 | 1 |
| 3 | + / Aitana feat. Cali & El Dandee | 6 | |
| 4 | Everything I wanted / Billie Eilish | 8 | 1 |
| 5 | Roxanne / Arizona Zervas | 9 | |
| 6 | Me gusta / Shakira & Anuel AA | 2 | |
| 7 | Adore you / Harry Styles | 6 | |
| 8 | My Oh My / Camila Cabello feat. DaBaby | 4 | |
| 9 | La mentira / Dani Martín | 9 | |
| 10 | A dónde vamos / Morat | 11 | |
| 11 | Before you go / Lewis Capaldi | 7 | |
| 12 | Yummy / Justin Bieber | 3 | |
| 13 | Luna / Lola Índigo | 7 | |
| 14 | Robarte el corazón / Bombai ft. Ana Guerra | 1 | |
| 15 | Future nostalgia / Dua Lipa | 2 | |
| 16 | Rare / Selena Gomez | 3 | |
| 17 | What a man gotta do / Jonas Brothers | 2 | |
| 18 | You should be sad (Lukkas Remix) / Halsey | 1 | |
| 19 | Underdog / Alicia Keys | 2 | |
| 20 | Alone (Pt. II) / Alan Walker & Ava Max | 4 | |
| 21 | Freaking me out / Ava Max | 8 | |
| 22 | Dosis / Dvicio ft. Reik & ChocQuibTown | 11 | |
| 23 | Casi / Melendi | 6 | |
| 24 | Una foto en blanco y negro / David Otero & Taburete | 1 | |
| 25 | Ritmo (Bad boys for life) / Black Eyed Peas & J Balvin | 13 | 1 |
| 26 | In your eyes / Robin Schulz ft. Alida | 2 | |
| 27 | Viene y va / C. Tangana & Natti Natasha | 1 | |
| 28 | Tabú / Pablo Alborán & Ava Max | 12 | 1 |
| 29 | Caída libre / Vanesa Martín | 11 | |
| 30 | Si por mi fuera / Beret | 14 | 1 |
| 31 | Lose control / Meduza x Becky Hill x GOODBOYS | 13 | |
| 32 | Nuestro tiempo / Amaral | 12 | 1 |
| 33 | We got love / Sigala ft. Ella Henderson | 9 | |
| 34 | Mother / Charlie Puth | 11 | |
| 35 | This is real / Jax Jones ft. Ella Henderson | 10 | |
| 36 | Tiburones / Ricky Martin | 1 | |
| 37 | Good as hell / Lizzo feat. Ariana Grande | 13 | |
| 38 | Ride it / Regard | 14 | 1 |
| 39 | Orphans / Coldplay | 13 | |
| 40 | Mama no / Pablo López | 8 |
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