The Weeknd y Daft Punk consiguen el último número uno del mes de octubre con 'Starboy'. Además hay 5 nuevas entradas en lista.
| Nº | AN | TÍTULO / ARTISTA | SE | MX |
| 1 | 4 | Starboy / The Weeknd feat Daft Punk | 6 | 1 |
| 2 | 3 | Vente pa' ca / Ricky Martin feat Maluma | 6 | 2 |
| 3 | 7 | 24k Magic / Bruno Mars | 4 | 3 |
| 4 | 2 | My way / Calvin Harris | 7 | 2 |
| 5 | 1 | Safari / J. Balvin ft Pharrell Williams | 8 | 1 |
| 6 | 5 | The greatest / Sia ft Kendrick Lamar | 8 | 1 |
| 7 | 9 | Verano / La oreja de Van Gogh | 7 | 6 |
| 8 | 8 | Antes que no / David Bisbal | 3 | 8 |
| 9 | 11 | Don't wanna know / Maroon 5 ft K. Lamar | 3 | 9 |
| 10 | 20 | Reggaetón lento (Bailemos) / CNCO | 2 | 10 |
| 11 | 6 | Heathens / Twenty One Pilots | 10 | 1 |
| 12 | 19 | Good life / Sweet California | 3 | 12 |
| 13 | 12 | Side to side / Ariana Grande ft N. Minaj | 8 | 12 |
| 14 | 18 | Love me now / John Legend | 4 | 14 |
| 15 | 17 | Love my life / Robbie Williams | 2 | 15 |
| 16 | 14 | Ain't my fault / Zara Larsson | 8 | 14 |
| 17 | 10 | Fuego / Juanes | 4 | 10 |
| 18 | 23 | Shout out to my ex / Little Mix | 2 | 18 |
| 19 | 13 | Would I lie to you / David Guetta & Cedric Gervais | 5 | 10 |
| 20 | 21 | Mercy / Shawn Mendes | 4 | 20 |
| 21 | 24 | That's my girl / Fifth Harmony | 3 | 21 |
| 22 | N | Chantaje / Shakira feat Maluma | 1 | 22 |
| 23 | 27 | I believe in you / Michael Bublé | 4 | 23 |
| 24 | N | Love on the brain / Rihanna | 1 | 24 |
| 25 | 15 | Closer / The Chainsmokers ft. Halsey | 13 | 1 |
| 26 | 31 | All night / The Vamps feat Matoma | 3 | 26 |
| 27 | 16 | Quiero que sepas / Juan Magán | 13 | 1 |
| 28 | N | Rockabye / Clean Bandit ft Sean Paul | 1 | 28 |
| 29 | 25 | This town / Niall Horan | 5 | 25 |
| 30 | 32 | Starving / Hailee Steinfeld & Grey ft Zedd | 2 | 30 |
| 31 | N | Drum / MØ | 1 | 31 |
| 32 | 29 | Sin contrato / Maluma | 7 | 28 |
| 33 | N | Scars to your beautiful / Alessia Cara | 1 | 33 |
| 34 | 26 | Body moves / DNCE | 5 | 22 |
| 35 | 22 | Desde que estamos juntos / Melendi | 6 | 13 |
| 36 | 35 | Meteorite / Years & Years | 7 | 22 |
| 37 | 28 | Perfect illusion / Lady Gaga | 8 | 9 |
| 38 | 34 | The ocean / Mike Perry ft Shy Martin | 9 | 14 |
| 39 | 37 | Carry me / Kygo | 5 | 36 |
| 40 | 36 | Hurts / Emeli Sandé | 7 | 18 |
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